Article
Characterization of anti-D monoclonal antibody reagents based on their reactivity with the weak D phenotype.
Transfusion - 1 May 2009
Lai Marco, Grasso Cinzia, Boschi Ilaria, D'Onofrio Giuseppe, Pascali Vincenzo, Leone Giuseppe
Abstract excerpt
BACKGROUND: Anti-D monoclonal antibody (MoAb) reagents have improved D typing in routine tests. However, they exhibit a wide range of reactivity with the weak D phenotype depending on the characteristics of the different MoAbs used. We analyzed the reactivity of immunoglobulin (IgM) anti-D by cluster analysis to characterize MoAb that have similar reactivities with the weak D phenotype. STUDY DESIGN AND METHODS:...
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