Article
Bioinformatic flowchart and database to investigate the origins and diversity of clan AA peptidases.
Biology direct - 27 Jan 2009
Llorens Carlos, Futami Ricardo, Renaud Gabriel, Moya Andrés
Abstract excerpt
BACKGROUND: Clan AA of aspartic peptidases relates the family of pepsin monomers evolutionarily with all dimeric peptidases encoded by eukaryotic LTR retroelements. Recent findings describing various pools of single-domain nonviral host peptidases, in prokaryotes and eukaryotes, indicate that the diversity of clan AA is larger than previously thought. The ensuing approach to investigate this enzyme group is by...
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