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Article

Usefulness of genetic polymorphisms and conventional risk factors to predict coronary heart disease in patients with familial hypercholesterolemia.

The American journal of cardiology - 1 Feb 2009

van der Net Jeroen B, Janssens A Cecile J W, Defesche Joep C, Kastelein John J P, Sijbrands Eric J G, Steyerberg Ewout W

Abstract excerpt

Familial hypercholesterolemia (FH) is an autosomal dominant disorder with an associated high risk of coronary heart disease (CHD). The considerable variation in age of onset of CHD in patients with FH is believed to arise from conventional risk factors, as well as genetic variation other than in the low-density lipoprotein receptor gene. The degree to which currently known genetic variants can improve the...

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Source

Identifiers

PMID: 19166692
DOI: 10.1016/j.amjcard.2008.09.093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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