Article
Dynamic patterns of human immunodeficiency virus type 1 integrase gene evolution in patients failing raltegravir-based salvage therapies.
AIDS (London, England) - 20 Feb 2009
Canducci Filippo, Sampaolo Michela, Marinozzi Maria Chiara, Boeri Enzo, Spagnuolo Vincenzo, Galli Andrea, Castagna Antonella, Lazzarin Adriano, Clementi Massimo, Gianotti Nicola
Abstract excerpt
OBJECTIVE: : Evaluate HIV-1 subtype B integrase gene evolution in patients failing raltegravir (RAL)-based savage regimens by clonal analysis of the replicating viral quasispecies. DESIGN: : Seven triple class failure HIV-1 (subtype B)-infected patients, followed at San Raffaele Hospital and enro...
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