Article
Tissue-specific RMA models to incrementally normalize Affymetrix GeneChip data.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jan 2008
Eschrich Steven A, Hoerter Andrew M, Bloom Gregory C, Fenstermacher David A
Abstract excerpt
Gene expression classifiers have been used to predict diagnosis of disease, patient prognosis and patient response to therapy. Although there have been remarkable successes in this area, a particular goal of personalized medicine is the ability predict a response from a single gene expression microarray. One aspect of this problem is the normalization of microarrays. Affymetrix GeneChip microarrays are typically...
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