Article
Early effects of lead on bone marrow cell responsiveness in mice challenged with Listeria monocytogenes.
Fundamental and applied toxicology : official journal of the Society of Toxicology - 1 Jul 1991
Kowolenko M, Tracy L, Lawrence D
Abstract excerpt
Listeria monocytogenes challenge of lead-treated mice results in increased mortality. Since macrophage development constitutes the initial phase of the immune response to L. monocytogenes, bone marrow and spleens from Pb-treated mice that were infected with L. monocytogenes were analyzed for their ability to form colonies when exposed to the macrophage growth factor CSF-1. Serum colony-stimulating activity also...
Topics
- Animals
- Bone Marrow
- Bone Marrow Cells
- Colony-Stimulating Factors
- Female
- Flow Cytometry
- Lead
- Listeria monocytogenes
- Listeriosis
- Liver
- Mice