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Article

Reduced expression of fukutin related protein in mice results in a model for fukutin related protein associated muscular dystrophies.

Brain : a journal of neurology - 1 Feb 2009

Ackroyd M R, Skordis L, Kaluarachchi M, Godwin J, Prior S, Fidanboylu M, Piercy R J, Muntoni F, Brown S C

Abstract excerpt

Mutations in fukutin related protein (FKRP) are responsible for a common group of muscular dystrophies ranging from adult onset limb girdle muscular dystrophies to severe congenital forms with associated structural brain involvement, including Muscle Eye Brain disease. A common feature of these disorders is the variable reduction in the glycosylation of skeletal muscle alpha-dystroglycan. In order to gain insight...

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Source

Identifiers

PMID: 19155270
DOI: 10.1093/brain/awn335

Genes

FKRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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