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Article

Inverse relationship between longevity and evolutionary rate of mitochondrial proteins in mammals and birds.

Mitochondrion - 1 Feb 2009

Galtier Nicolas, Blier Pierre U, Nabholz Benoit

Abstract excerpt

Recently, an unexpected, positive correlation between the rate of evolution of mitochondrial proteins and longevity was reported. Here we re-analyze this relationship in various mammalian lineages using a bayesian phylogenetic analysis of amino-acid sequences, allowing for variable evolutionary rates across sites and species. A negative relationship between protein evolutionary rate and species longevity is...

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PMID: 19154799
DOI: 10.1016/j.mito.2008.11.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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