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Article

RNA polymerase I can mediate expression of CAT and neo protein-coding genes in Trypanosoma brucei.

The EMBO journal - 1 Nov 1991

Rudenko G, Chung H M, Pham V P, Van der Ploeg L H

Abstract excerpt

We show that the ribosomal RNA (rRNA) promoter can efficiently direct expression of protein-coding genes in the parasitic protozoan Trypanosoma brucei. The rRNA promoter was characterized by: (i) point mutations at the rRNA transcription initiation site which completely abolished its promoter function in transient CAT transformation assays; (ii) the alpha-amanitin resistance of transcription of rRNA...

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Identifiers

PMID: 1915299
DOI: 10.1002/j.1460-2075.1991.tb04903.x
PMCID: PMC453067

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RNA polymerase I can mediate expression of CAT and neo protein-coding genes in Trypanosoma brucei.PMID 1915299Read ↗

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