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Article

NF-kappaB links keratinocytes and lymphocytes in the pathogenesis of psoriasis.

Recent patents on inflammation & allergy drug discovery - 1 Jan 2009

Tsuruta Daisuke

Abstract excerpt

Psoriasis is a common, chronic and relapsing autoimmune skin disease. Clinical characteristics of this disease are sharply-demarcated erythematous plaques covered with silver scales. Histologically, it is characterized by increased epidermal thickness, elongated papillae, and a moderate inflammatory infiltrate composed of lymphocytes, macrophages and neutrophils. The histological hallmark of psoriasis is Munro's...

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Identifiers

PMID: 19149745
DOI: 10.2174/187221309787158399

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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