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Article

Misbehaving macrophages in the pathogenesis of psoriasis

1 Aug 2006

Abstract excerpt

Psoriasis is a chronic inflammatory skin disease unique to humans. In this issue of the JCI, 2 studies of very different mouse models of psoriasis both report that macrophages play a key role in inducing psoriasis-like skin disease. Psoriasis is clearly a polygenic, inherited disease of uncontrolled cutaneous inflammation. The debate that currently rages in the field is whether psoriasis is a disease of...

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Share to Cytokine Signaling Pathways and Interactions
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PMID: 16886055
DOI: 10.1172/jci29441

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