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Article

Hypertension genes and retinal vascular calibre: the Cardiovascular Health Study.

Journal of human hypertension - 1 Sept 2009

Sun C, Wang J J, Islam F M, Heckbert S R, Klein R, Siscovick D S, Klein B E K, Wong T Y

Abstract excerpt

We examined the associations of single nucleotide polymorphisms (SNPs) in three candidate hypertension genes, alpha-adducin (ADD1/G460W), beta2-adrenergic receptor (ADRB2/Arg16Gly and Gln27Glu) and G-protein beta3 subunit (GNB3/C825T), with retinal arteriolar calibre (an intermediate marker of chronic hypertension) and venular calibre. Data in 1842 participants (1554 whites and 288 African Americans) aged 69-96...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19148102
DOI: 10.1038/jhh.2008.168
PMCID: PMC2888043

Genes

ADD1
GNB3
ADRB2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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