Article
Assessing the Causality between Blood Pressure and Retinal Vascular Caliber through Mendelian Randomisation.
Scientific reports - 25 Feb 2016
Li Ling-Jun, Liao Jiemin, Cheung Carol Yim-Lui, Ikram M Kamran, Shyong Tai E, Wong Tien-Yin, Cheng Ching-Yu
Abstract excerpt
We aimed to determine the association between blood pressure (BP) and retinal vascular caliber changes that were free from confounders and reverse causation by using Mendelian randomisation. A total of 6528 participants from a multi-ethnic cohort (Chinese, Malays, and Indians) in Singapore were included in this study. Retinal arteriolar and venular caliber was measured by a semi-automated computer program....
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