Article
Genetic loci for retinal arteriolar microcirculation.
PloS one - 1 Jan 2013
Sim Xueling, Jensen Richard A, Ikram M Kamran, Cotch Mary Frances, Li Xiaohui, MacGregor Stuart, Xie Jing, Smith Albert Vernon, Boerwinkle Eric, Mitchell Paul, Klein Ronald, Klein Barbara E K, Glazer Nicole L, Lumley Thomas, McKnight Barbara, Psaty Bruce M, de Jong Paulus T V M, Hofman Albert, Rivadeneira Fernando, Uitterlinden Andre G, van Duijn Cornelia M, Aspelund Thor, Eiriksdottir Gudny, Harris Tamara B, Jonasson Fridbert, Launer Lenore J, Attia John, Baird Paul N, Harrap Stephen, Holliday Elizabeth G, Inouye Michael, Rochtchina Elena, Scott Rodney J, Viswanathan Ananth, Li Guo, Smith Nicholas L, Wiggins Kerri L, Kuo Jane Z, Taylor Kent D, Hewitt Alex W, Martin Nicholas G, Montgomery Grant W, Sun Cong, Young Terri L, Mackey David A, van Zuydam Natalie R, Doney Alex S F, Palmer Colin N A, Morris Andrew D, Rotter Jerome I, Tai E Shyong, Gudnason Vilmundur, Vingerling Johannes R, Siscovick David S, Wang Jie Jin, Wong Tien Y
Abstract excerpt
Narrow arterioles in the retina have been shown to predict hypertension as well as other vascular diseases, likely through an increase in the peripheral resistance of the microcirculatory flow. In this study, we performed a genome-wide association study in 18,722 unrelated individuals of European...
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