Article
Tas1R1-Tas1R3 taste receptor variants in human fungiform papillae.
Neuroscience letters - 27 Feb 2009
Raliou Mariam, Boucher Yves, Wiencis Anna, Bézirard Valérie, Pernollet Jean-Claude, Trotier Didier, Faurion Annick, Montmayeur Jean-Pierre
Abstract excerpt
Monosodium glutamate as well as metabotropic and ionotropic glutamate receptor agonists have been reported to be perceived as umami by humans. In spite of the fact that Tas1R1-Tas1R3 has been shown to mediate most of the glutamate taste sensation in mice other candidate receptors have been put forward for which a clear role in detection is still lacking. This work was aimed at investigating the molecular...
Topics
- Adult
- Aged
- Allosteric Regulation
- Binding Sites
- Female
- Genetic Variation
- Glutamic Acid
- Humans
- Ligands
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
