Article
Nonsynonymous single nucleotide polymorphisms in human tas1r1, tas1r3, and mGluR1 and individual taste sensitivity to glutamate.
The American journal of clinical nutrition - 1 Sept 2009
Raliou Mariam, Wiencis Anna, Pillias Anne-Marie, Planchais Aurore, Eloit Corinne, Boucher Yves, Trotier Didier, Montmayeur Jean-Pierre, Faurion Annick
Abstract excerpt
Several studies indicate an essential role of the heterodimer Tas1R1-Tas1R3 for monosodium l-glutamate (MSG) detection, although others suggest alternative receptors. Human subjects show different taste sensitivities to MSG, and some are unable to detect the presence of glutamate. Our objective w...
Topics
- Base Sequence
- Female
- France
- Gene Expression
- Genotype
- Humans
- Male
- Phenotype
- Polymorphism, Single Nucleotide
- Receptors, G-Protein-Coupled
- Receptors, Glutamate
- Receptors, Metabotropic Glutamate
- Reverse Transcriptase Polymerase Chain Reaction