Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spontaneous and cytokine induced expression and activity of matrix metalloproteinases in human colonic epithelium

27 Nov 2008

Abstract excerpt

Matrix metalloproteinases (MMPs) have been implicated in tissue damage associated with inflammatory bowel disease (IBD).As the role of the intestinal epithelium in this process is unknown, we determined MMP expression and enzyme activity in human colonic epithelial cells (CEC). MMP mRNA expression was assessed by reverse transcription-polymerase chain reaction in HT-29 and DLD-1 cells and in CEC isolated from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Peptidase Inhibition and Analysis
Share to Protease and Inhibitor Mechanisms
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19137636
DOI: 10.1111/j.1365-2249.2008.03836.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Spontaneous and cytokine induced expression and activity of matrix metalloproteinases in human colonic epitheliumPMID 19137636Read ↗

Matrix metalloproteinases in inflammatory bowel disease: an update.Semantic proximity Read ↗

Increased mucosal matrix metalloproteinase-1, -2, -3 and -9 activity in patients with inflammatory bowel disease and the relation with Crohn's disease phenotype.Semantic proximity Read ↗

Effect of the anti-tumor necrosis factor-alpha antibody infliximab on the ex vivo mucosal matrix metalloproteinase-proteolytic phenotype in inflammatory bowel disease.Semantic proximity Read ↗

Characterization of myofibroblasts isolated from the intestine of patients with inflammatory bowel diseaseSemantic proximity Read ↗

Infliximab Restores the Dysfunctional Matrix Remodeling Protein and Growth Factor Gene Expression in Patients with Inflammatory Bowel DiseaseSemantic proximity Read ↗

Spectrum of Cytokine Gene Expression in Intestinal Mucosal Lesions of Crohn’s Disease and Ulcerative ColitisSemantic proximity Read ↗

The molecular biology of matrix metalloproteinases and tissue inhibitors of metalloproteinases in inflammatory bowel diseasesSemantic proximity Read ↗

Recent understanding of IBD pathogenesis: implications for future therapies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.