Article
Crystal structure of the dimerization domain of human filamin A
24 Nov 2008
Abstract excerpt
Reorganization of actin cytoskeleton plays a central role in many cell functions such as the maintenance of cell shape, cell division, cell locomotion, and phagocytosis.1 Filamins are actin-crosslinking proteins that give mechanical force to cells by binding to actin filaments and making the filamentous actin form bundles or gel networks.1 Filamin is also involved in various cellular processes by anchoring...
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