Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparing techniques for the identification of the MTHFR A1298C polymorphism.

Journal of biomolecular techniques : JBT - 1 Apr 2008

de Alvarenga Maria Paula Sanches, Pavarino-Bertelli Erika Cristina, Goloni-Bertollo Eny Maria

Abstract excerpt

The restriction fragment length polymorphism (RFLP) technique with the MboII enzyme is used by a number of researchers as a methodology for the identification of the genetic polymorphism MTHFR A1298C. However, the reliability of this enzyme for genotyping this polymorphism has been questioned, since the silent polymorphism T1317C, located close to the polymorphic region A1298C on gene MTHFR, also has a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Biotechnology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brazil

Share to Deoxyribonucleases, Type II Site-Specific

Share to DNA Primers

Share to Kidney Transplantation

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Restriction Fragment Length

Source

Open in PubMed Open full text

Identifiers

PMID: 19137091
PMCID: PMC2361162

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Comparing techniques for the identification of the MTHFR A1298C polymorphism.PMID 19137091Read ↗

MTHFR C677T polymorphism analysis: A simple, effective restriction enzyme‐based method improving previous protocolsSemantic proximity Read ↗

A new and improved method based on polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) for the determination of A1298C mutation in the methylenetetrahydrofolate reductase (MTHFR) gene.Semantic proximity Read ↗

A common 1317TC polymorphism in MTHFR can lead to erroneous 1298AC genotyping by PCR-RE and TaqMan probe assays.Semantic proximity Read ↗

[Detecting MTHFR gene mutation with a new approach: molecular beacons].Semantic proximity Read ↗

Patterns of co-occurrence of three single nucleotide polymorphisms of the 5,10-methylenetetrahydrofolate reductase gene in kidney transplant recipients.Semantic proximity Read ↗

Development of a highly accurate, rapid PCR-RFLP genotyping assay for the methylenetetrahydrofolate reductase gene.Semantic proximity Read ↗

Analysis of factor VIII gene polymorphisms in Brazilian blacks reveals further differences in the black population.Semantic proximity Read ↗

Development of an internal restriction control in the PCR detection of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.