Article
Androgen sensitivity of the new human breast cancer cell line MFM-223.
Cancer research - 15 Oct 1991
Hackenberg R, Lüttchens S, Hofmann J, Kunzmann R, Hölzel F, Schulz K D
Abstract excerpt
The mammary carcinoma cell line MFM-223 is characterized by high androgen and low estrogen and progesterone receptor levels. With the dextran charcoal method, androgen binding was determined at 160 fmol/mg protein corresponding to approximately 100,000 binding sites per cell in whole cell binding assays. The estrogen and progesterone receptor contents were between 8 and 18 fmol/mg protein. The proliferation of...
Topics
- Breast Neoplasms
- Cell Division
- Dihydrotestosterone
- Humans
- Karyotyping
- Phenotype
- Receptors, Androgen
- Receptors, Estrogen
- Tumor Cells, Cultured