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Article

CYP1, a hypovirus-regulated cyclophilin, is required for virulence in the chestnut blight fungus.

Molecular plant pathology - 1 Apr 2011

Chen Min-Mei, Jiang Mingguo, Shang Jinjie, Lan Xiuwan, Yang Feng, Huang Jingkuan, Nuss Donald L, Chen Baoshan

Abstract excerpt

Cyclophilins are peptidyl-prolyl cis-trans isomerases that are highly conserved throughout eukaryotes and are the cellular target of the immunosuppressive drug cyclosporin A (CsA). We cloned cyp1, a cyclophilin A-encoding gene in the phytopathogenic fungus Cryphonectria parasitica, and showed that this gene was downregulated following infection by a virulence-attenuating hypovirus. The function of cyp1 was...

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Identifiers

PMID: 21355996
DOI: 10.1111/j.1364-3703.2010.00665.x
PMCID: PMC3313458

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CYP1, a hypovirus-regulated cyclophilin, is required for virulence in the chestnut blight fungus.PMID 21355996Read ↗

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