Article
Hypovirulence-associated traits induced by a mycovirus of Cryphonectria parasitica are mimicked by targeted inactivation of a host gene.
Molecular and cellular biology - 1 Dec 1993
Zhang L, Churchill A C, Kazmierczak P, Kim D H, Van Alfen N K
Abstract excerpt
Expression of the Vir2 gene of Cryphonectria parasitica is down-regulated in strains of the fungus containing a double-stranded RNA genetic element that reduces fungal virulence (W. A. Powell and N. K. Van Alfen, Mol. Cell. Biol. 7:3688-3693, 1987). We have sequenced the Vir2 gene and characteriz...
Topics
- Amino Acid Sequence
- Ascomycota
- Base Sequence
- DNA, Fungal
- Down-Regulation
- Gene Amplification
- Gene Expression
- Genes, Fungal
- Genes, Mating Type, Fungal
- Genes, Viral
- Molecular Sequence Data
- Mutation
- Phenotype
- RNA, Double-Stranded
- RNA, Fungal
- RNA, Messenger
- Transcription, Genetic
- Virulence