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Article

The G11778A LHON mutation does not enhance ethambutol cytotoxicity in a cybrid model.

Clinical neuropathology - 1 Jan 2000

Pommer R, Schoeler S, Mawrin C, Szibor R, Kirches E

Abstract excerpt

UNLABELLED: Leber's hereditary optic neuropathy (LHON) is a maternally inherited mitochondrial disorder, leading to a selective loss of retinal ganglion cells (RGC) and degeneration of the optic nerve, which results in severe visual impairment or even blindness. The primary causes are point mutations of the mitochondrial DNA (mtDNA), associated with aminoacid exchanges in complex I of the electron transport chain...

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Source

Identifiers

PMID: 19130740
DOI: 10.5414/npp27414

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The G11778A LHON mutation does not enhance ethambutol cytotoxicity in a cybrid model.PMID 19130740Read ↗

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