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Article

Revertant somatic mosaicism in the Wiskott-Aldrich syndrome.

Immunologic research - 1 Jan 2009

Davis Brian R, Candotti Fabio

Abstract excerpt

Up to 11% of patients affected with Wiskott-Aldrich syndrome (WAS) have presented with somatic mosaicism due to spontaneous in vivo reversion to normal of the original mutation or second-site compensatory mutations that restored production of the WAS gene product. The reasons underlying the high prevalence of this phenomenon in WAS are unclear and may include strong selective advantage of revertant cells over...

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Identifiers

PMID: 19129986
DOI: 10.1007/s12026-008-8091-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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