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Article

Unprecedented diversity of genotypic revertants in lymphocytes of a patient with Wiskott-Aldrich syndrome.

Blood - 15 May 2008

Davis Brian R, Dicola Michael J, Prokopishyn Nicole L, Rosenberg Jonathan B, Moratto Daniele, Muul Linda M, Candotti Fabio, Michael Blaese R

Abstract excerpt

Spontaneous somatic reversions of inherited mutations are poorly understood phenomena that are thought to occur uncommonly in a variety of genetic disorders. When molecularly characterized, revertant cells have rarely exhibited more than one revertant genotype per patient. We analyzed individual allospecific T-cell clones derived from a Wiskott-Aldrich syndrome (WAS) patient identified by flow cytometry to have...

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Identifiers

PMID: 18332229
DOI: 10.1182/blood-2007-06-095299
PMCID: PMC2384133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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