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Article

Somatic mosaicism in the Wiskott-Aldrich syndrome: molecular and functional characterization of genotypic revertants.

Clinical immunology (Orlando, Fla.) - 1 Apr 2010

Davis Brian R, Yan Qing, Bui Jacquelin H, Felix Kumar, Moratto Daniele, Muul Linda M, Prokopishyn Nicole L, Blaese R Michael, Candotti Fabio

Abstract excerpt

The reasons underlying the occurrence of multiple revertant genotypes in Wiskott-Aldrich syndrome (WAS) patients remain unclear. We have identified more than 30 revertant genotypes in a C995T WAS patient having 10-15% revertant, WAS protein (WASp)-expressing circulating lymphocytes. Of 497 allosp...

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Identifiers

PMID: 20123155
DOI: 10.1016/j.clim.2009.12.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20123155-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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