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Article

A gene expression signature shared by human mature oocytes and embryonic stem cells

8 Jan 2009

Abstract excerpt

BACKGROUND: The first week of human pre-embryo development is characterized by the induction of totipotency and then pluripotency. The understanding of this delicate process will have far reaching implication for in vitro fertilization and regenerative medicine. Human mature MII oocytes and embryonic stem (ES) cells are both able to achieve the feat of cell reprogramming towards pluripotency, either by somatic...

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PMID: 19128516
DOI: 10.1186/1471-2164-10-10

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