Article
Convergent genome wide association results for bipolar disorder and substance dependence.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2009
Johnson Catherine, Drgon Tomas, McMahon Francis J, Uhl George R
Abstract excerpt
Twin studies document substantial heritability for substance dependence and bipolar disorder [Shih et al. (2004); Uhl et al. (2008a)]. Individuals with bipolar disorder display substance use disorders at rates that are much higher than those in the general population [Krishnan (2005)]. We would thus predict: 1) substantial overlap between different genome wide association (GWA) studies of bipolar disorder 2)...
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