Article
Capillary electrophoresis of recombinant proteins.
Journal of chromatography. B, Biomedical sciences and applications - 12 Sept 1997
Denton K A, Tate S A
Abstract excerpt
Many naturally occurring proteins which are used therapeutically have been cloned and expressed in large quantities in bacterial, yeast or mammalian systems. Purification of these proteins by column chromatography generates high purity products with low levels of host protein contaminants. However, isoforms of the desired protein may be present at variable concentrations. Analysis of these variant forms has been...
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