Article
Examination of the current top candidate genes for AD in a genome-wide association study.
Molecular psychiatry - 1 Jul 2010
Feulner T M, Laws S M, Friedrich P, Wagenpfeil S, Wurst S H R, Riehle C, Kuhn K A, Krawczak M, Schreiber S, Nikolaus S, Förstl H, Kurz A, Riemenschneider M
Abstract excerpt
With the advent of technologies that allow simultaneous genotyping of thousands of single-nucleotide polymorphisms (SNPs) across the genome, the genetic contributions to complex diseases can be explored at an unprecedented detail. This study is among the first to apply the genome-wide association study (GWAS) approach to Alzheimer disease (AD). We present our GWAS results from the German population for genes...
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