Susceptibility to verotoxin as a function of the cell cycle.

doi:10.1002/jcp.1041500324

Back to search

Article

Susceptibility to verotoxin as a function of the cell cycle.

Journal of cellular physiology - 1 Mar 1992

Pudymaitis A, Lingwood C A

Abstract excerpt

Infection with Verotoxin producing Escherichia coli (VTEC) has been implicated in hemolytic uremic syndrome, the leading cause of pediatric renal failure. Verotoxin (VT) binds to globotriaosylceramide (Gal alpha 1-4Gal beta 1-4GlcCer Gb3) in susceptible cells. Gb3 is required for cytotoxicity and...

Topics

Animals
Bacterial Toxins
Cell Cycle
Cell Division
Chromatography, High Pressure Liquid
Cytotoxins
Drug Resistance
Humans
Microscopy, Fluorescence
Mutation
Shiga Toxin 1
Trihexosylceramides
Vero Cells

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.