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Article

DNA methylation and mRNA expression of SYN III, a candidate gene for schizophrenia.

BMC medical genetics - 22 Dec 2008

Murphy Brenda C, O'Reilly Richard L, Singh Shiva M

Abstract excerpt

BACKGROUND: The synapsin III (SYN III) gene on chromosome 22q is a candidate gene for schizophrenia susceptibility due to its chromosome location, neurological function, expression patterns and functional polymorphisms. METHODS: This research has established the mRNA expression of SYN III in 22 adult human brain regions as well as the methylation specificity in the closest CpG island of this gene. The methylation...

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Identifiers

PMID: 19102774
DOI: 10.1186/1471-2350-9-115
PMCID: PMC2630979

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