The Mycobacterium tuberculosis shikimate pathway genes: evolutionary relationship between biosynthetic and catabolic 3-dehydroquinases.

doi:10.1007/BF00260631

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Article

The Mycobacterium tuberculosis shikimate pathway genes: evolutionary relationship between biosynthetic and catabolic 3-dehydroquinases.

Molecular & general genetics : MGG - 1 Sept 1991

Garbe T, Servos S, Hawkins A, Dimitriadis G, Young D, Dougan G, Charles I

Abstract excerpt

The Mycobacterium tuberculosis shikimate pathway genes designated aroB and aroQ encoding 3-dehydroquinate synthase and 3-dehydroquinase, respectively were isolated by molecular cloning and their nucleotide sequences determined. The deduced dehydroquinate synthase amino acid sequence from M. tuberculosis showed high similarity to those of equivalent enzymes from prokaryotes and filamentous fungi. Surprisingly, the...

Topics

Amino Acid Sequence
Base Sequence
Biological Evolution
Electrophoresis, Agar Gel
Electrophoresis, Polyacrylamide Gel
Escherichia coli
Genes, Bacterial
Hydro-Lyases
Isoenzymes
Lyases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Mycobacterium tuberculosis

Phosphorus-Oxygen Lyases

Restriction Mapping

Sequence Homology, Nucleic Acid

Shikimic Acid

Source

Open in PubMed

Identifiers

PMID: 1910148
DOI: 10.1007/BF00260631

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1910148-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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