Article
Differential flux through the quinate and shikimate pathways. Implications for the channelling hypothesis.
The Biochemical journal - 15 May 1992
Lamb H K, van den Hombergh J P, Newton G H, Moore J D, Roberts C F, Hawkins A R
Abstract excerpt
The qutC gene encoding dehydroshikimate dehydratase has been constitutively overexpressed in Aspergillus nidulans from a range of 1-30-fold over the normal wild-type level. This overexpression leads to impaired growth in minimal medium which can be alleviated by the addition of aromatic amino aci...
Topics
- Alcohol Oxidoreductases
- Amino Acids
- Aspergillus nidulans
- Gene Expression
- Genetic Variation
- Hydro-Lyases
- Hydroxybenzoates
- Lyases
- Multienzyme Complexes
- Phosphotransferases
- Phosphotransferases (Alcohol Group Acceptor)
- Plasmids
- Quinic Acid
- Shikimic Acid
- Transferases