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Article

New genetic abnormalities and treatment response in acute lymphoblastic leukemia.

Seminars in hematology - 1 Jan 2009

Meijerink Jules P P, den Boer Monique L, Pieters Rob

Abstract excerpt

Numerous genetic abnormalities have been identified in acute lymphoblastic leukemia (ALL). Here we review the recurrent abnormalities with emphasis on those recently discovered, and discuss their association with chemotherapy resistance or sensitivity and with clinical response to therapy. Also, the role of genetic abnormalities in leukemogenesis and their potential as therapeutic targets will be discussed.

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Identifiers

PMID: 19100364
DOI: 10.1053/j.seminhematol.2008.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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