Article
[The relationship between the effect of amlodipine on carotid intimal-medial thickness and angiotensin converting enzyme genotypes in elderly hypertensive patients].
Zhonghua xin xue guan bing za zhi - 1 Jun 2008
Zhai Li-hua, Wang Sha-yan, Liang Xu, Yang Chun-yu, Zhang Ruan-zhang, Wang Zeng-ying, Tang Jun, Hu Yu-hua
Abstract excerpt
OBJECTIVE: To investigate the association between the anti-atherosclerotic effects of amlodipine and angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism in elderly essential hypertensive (EH) patients. METHODS: A total of 220 EH patients were treated with amlodipine (2.5 - 10 mg, once daily) for twelve months and complete data were obtained from 208 patients with genotypes of II (n =...
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