Article
Relationship of angiotensin-converting enzyme gene polymorphism to carotid wall thickness in middle-aged men.
Journal of molecular medicine (Berlin, Germany) - 1 Dec 1999
Huang X H, Loimaala A, Nenonen A, Mercuri M, Vuori I, Pasanen M, Oja P, Bond G, Koivula T, Hiltunen T P, Nikkari T, Lehtimäki T
Abstract excerpt
The insertion/deletion (I/D) polymorphism of the human angiotensin-converting enzyme (ACE) gene is a major determinant of circulating ACE levels. The D allele has been suggested to be a potent risk factor for coronary artery disease; however, the effect of the ACE gene on carotid atherosclerosis remains controversial. We therefore studied the relationship between the ACE gene I/D polymorphism and carotid artery...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.