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Article

Involvement of SMRT Corepressor in Transcriptional Repression by the Vitamin D Receptor

19 Dec 2008

Abstract excerpt

To repress the expression of target genes, the unliganded nuclear receptor generally recruits the silencing mediator of retinoid and thyroid hormone receptor (SMRT)/nuclear receptor corepressor via its direct association with the conserved motif within bipartite nuclear receptor-interaction domains (IDs) of the corepressor. Here, we investigated the involvement of the SMRT corepressor in transcriptional...

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PMID: 19098224
DOI: 10.1210/me.2008-0426

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