Article
Repair of Osteochondral Defects With Predifferentiated Mesenchymal Stem Cells of Distinct Phenotypic Character Derived From a Nanotopographic Platform.
The American journal of sports medicine - 1 Jun 2020
Wu Yingnan, Yang Zheng, Denslin Vinitha, Ren XiaFei, Lee Chang Sheng, Yap Fung Ling, Lee Eng Hin
Abstract excerpt
BACKGROUND: Articular cartilage has a zonal architecture and biphasic mechanical properties. The recapitulation of surface lubrication properties with high compressibility of the deeper layers of articular cartilage during regeneration is essential in achieving long-term cartilage integrity. Current clinical approaches for cartilage repair, especially with the use of mesenchymal stem cells (MSCs), have yet to...
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