Article
Screening of common CYP1B1 mutations in Iranian POAG patients using a microarray-based PrASE protocol.
Molecular vision - 1 Jan 2008
Suri Fatemeh, Kalhor Reza, Zargar Seyed Jalal, Nilforooshan Navid, Yazdani Shahin, Nezari Hossein, Paylakhi Seyed Hassan, Narooie-Nejhad Mehrnaz, Bayat Behnaz, Sedaghati Tina, Ahmadian Afshin, Elahi Elahe
Abstract excerpt
PURPOSE: The gene coding cytochrome P4501B1 (CYP1B1) has been shown to be a major cause of primary congenital glaucoma in the Iranian population. More recently it was shown to also be important in juvenile-onset open angle glaucoma (JOAG). We aimed to further investigate the role of CYP1B1 in a larger cohort of primary open angle glaucoma (POAG) patients which included late-onset patients. We also aimed to set up...
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