Article
Identification of novel CYP1B1 gene mutations in patients with primary congenital and primary open-angle glaucoma.
Clinical & experimental ophthalmology - 1 Jan 2000
Micheal Shazia, Ayub Humaira, Zafar Saemah N, Bakker Bjorn, Ali Mahmood, Akhtar Farah, Islam Farrah, Khan Muhammad I, Qamar Raheel, den Hollander Anneke I
Abstract excerpt
BACKGROUND: CYP1B1 is the most commonly mutated gene in primary congenital glaucoma (PCG), and mutations have also been identified in primary open-angle glaucoma (POAG). This study was undertaken to describe mutations in CYP1B1 in patients and families with PCG and POAG from Pakistan. DESIGN: Case-control series. PARTICIPANTS: Forty families, 190 sporadic POAG cases and 140 controls from Pakistan. METHODS:...
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