Article
[Genetic polymorphism of growth hormone gene in adolescent idiopathic scoliosis].
Zhonghua wai ke za zhi [Chinese journal of surgery] - 15 Nov 2008
Qiu Xu-sheng, Deng Liang-sheng, Yang Xiao-en, Zheng Zhen-yao, Qiu Yong
Abstract excerpt
OBJECTIVE: To investigate whether the growth hormone gene (GH) promotor polymorphism (rs2854184) is associated with the occurrence or curve severity of adolescent idiopathic scoliosis (AIS). METHODS: Two hundred and sixty-five AIS patients and 193 normal controls were recruited. The maximum Cobb angles were recorded in AIS patients. PCR-RFLP was used for the genotyping. RESULTS: The genotype frequency...
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