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Article

Nuclear inner membrane fusion facilitated by yeast Jem1p is required for spindle pole body fusion but not for the first mitotic nuclear division during yeast mating.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Nov 2008

Nishikawa Shuh-ichi, Hirata Aiko, Endo Toshiya

Abstract excerpt

During mating of budding yeast, Saccharomyces cerevisiae, two haploid nuclei fuse to produce a diploid nucleus. The process of nuclear fusion requires two J proteins, Jem1p in the endoplasmic reticulum (ER) lumen and Sec63p, which forms a complex with Sec71p and Sec72p, in the ER membrane. Zygotes of mutants defective in the functions of Jem1p or Sec63p contain two haploid nuclei that were closely apposed but...

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Identifiers

PMID: 19090812
DOI: 10.1111/j.1365-2443.2008.01236.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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