Article
Malignant cell detection in Burkitt's lymphoma using third-complementarity-determining region (CDRIII), clone-specific probe developed by sequencing DNA from stored slides.
Japanese journal of cancer research : Gann - 1 Jul 1991
Asada M, Miyashita T, Bessho F, Kobayashi N, Mizutani S
Abstract excerpt
The DNA sequence of the third-complementarity-determining region (CDRIII) of the immunoglobulin heavy chain (IgH) gene in a case of Burkitt's lymphoma was determined by polymerase chain reaction (PCR) using template DNA extracted from a smear stored at room temperature for more than one year. The...
Topics
- Base Sequence
- Bone Marrow
- Burkitt Lymphoma
- Cell Transformation, Neoplastic
- Cloning, Molecular
- DNA
- DNA Probes
- Female
- Humans
- Immunoglobulin Heavy Chains
- Immunoglobulin Variable Region
- Male
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction