Article
Extent of genome-wide linkage disequilibrium in Australian Holstein-Friesian cattle based on a high-density SNP panel.
BMC genomics - 24 Apr 2008
Khatkar Mehar S, Nicholas Frank W, Collins Andrew R, Zenger Kyall R, Cavanagh Julie A L, Barris Wes, Schnabel Robert D, Taylor Jeremy F, Raadsma Herman W
Abstract excerpt
BACKGROUND: The extent of linkage disequilibrium (LD) within a population determines the number of markers that will be required for successful association mapping and marker-assisted selection. Most studies on LD in cattle reported to date are based on microsatellite markers or small numbers of single nucleotide polymorphisms (SNPs) covering one or only a few chromosomes. This is the first comprehensive study on...
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