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Article

Evaluation of mitochondrial DNA coding region assays for increased discrimination in forensic analysis.

Forensic science international. Genetics - 1 Jan 2008

Nilsson Martina, Andréasson-Jansson Hanna, Ingman Max, Allen Marie

Abstract excerpt

There is an increasing trend to use mitochondrial DNA (mtDNA) analysis in criminal investigations where only limited amounts of DNA are available. However, analysis of the mtDNA control region has the drawback of low discrimination power, due to the lack of recombination that results from uniparental (maternal) inheritance. As a strategy to increase discrimination, a number of typing assays detecting variation in...

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Identifiers

PMID: 19083783
DOI: 10.1016/j.fsigen.2007.07.004

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