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Article

Telomere uncapping during <i>in vitro</i> T‐lymphocyte senescence

11 Dec 2008

Abstract excerpt

Normal lymphocytes represent examples of somatic cells that are able to induce telomerase activity when stimulated. As previously reported, we showed that, during lymphocyte long-term culture and repeated stimulations, the appearance of senescent cells is associated with telomere shortening and a progressive drop in telomerase activity. We further showed that this shortening preferentially occured at long...

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Share to Telomeres, Telomerase, and Senescence

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19077045
DOI: 10.1111/j.1474-9726.2008.00448.x

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