Multinuclear Magnetic Resonance Spectroscopy for <i>in Vivo</i> Assessment of Mitochondrial Dysfunction in Parkinson's Disease

Abstract excerpt

Parkinson's disease (PD) is a common and often devastating neurodegenerative disease affecting up to one million individuals in the United States alone. Multiple lines of evidence support mitochondrial dysfunction as a primary or secondary event in PD pathogenesis; a better understanding, therefore, of how mitochondrial function is altered in vivo in brain tissue in PD is a critical step toward developing...

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