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Article

Increasing the number of SNP loci does not necessarily improve prediction power at least in the comparison of MTHFR SNP and haplotypes.

Journal of epidemiology - 1 Jan 2008

Miyaki Koichi, Takahashi Yoshimitsu, Song Yixuan, Zhang Ling, Muramatsu Masaaki, Nakayama Takeo

Abstract excerpt

BACKGROUND: Rapid advances in genotyping technology have made it possible to easily utilize a large number of genetic markers. According to information theory, an increase in the number of markers provides more information; however, the clinical usefulness does not increase linearly. This study aimed to assess the effect of folic acid supplementation quantitatively in MTHFR haplotypes, and compare its prediction...

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Identifiers

PMID: 19075497
DOI: 10.2188/jea.je2008022
PMCID: PMC4771609

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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