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Article

Regulation of the ankyrin-B-based targeting pathway following myocardial infarction

14 Dec 2008

Abstract excerpt

AIMS: Ion channel reorganization is a critical step in the pro-arrhythmogenic remodelling process that occurs in heart disease. Ankyrin-B (AnkB) is required for targeting and stabilizing ion channels, exchangers, and pumps. Despite a wealth of knowledge implicating the importance of AnkB in human cardiovascular physiology, nothing is known regarding the role of AnkB in common forms of acquired human disease....

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PMID: 19074823
DOI: 10.1093/cvr/cvn348

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